because this hypothetical scenario is totally possible:

Oncology student rounds:

Clinician: "Okay, what are the five front-line drugs for treating lymphoma?"

Students: "Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and L-asparaginase."

Clinician: "So if you were going to randomly not use one of those drugs, which one would you eliminate?"

Students: "Why?"

Clinician: "You're traveling to a desert island.  You have 100 dogs with lymphoma, and you only have room for four drugs per dog.  Which one do you leave behind?"

Students:  "..."

(In case you were wondering, the answer is L-asparaginase)